Matthew or Matthews could refer to:
- People
- Matthew, a 24th century native of Danula II
- Matthews, a crewman aboard the USS Enterprise in the 2260s
- Matthew Adamson, a casualty of Earth's Vietnam War
- Matthew Alford, a commander aboard the USS Enterprise in 2268
- Matthew Barnes, an engineer aboard the Enterprise-D
- Matthew Blumberg, a 23rd century archeologist
- Matthew Brady, a notable photo journalist during the American Civil War
- Matthew Chiavelli, security chief of the USS Musashi in 2379
- Matthew Decker, a 23rd century Starfleet commodore, CO of the USS Constellation
- Matthew Decker (mirror), grand admiral of the Imperial Starfleet
- Matthew Decker (24th century), great grandson of Matthew Decker
- Matthew Dougherty, a 24th century Starfleet vice admiral
- Matthew Falce, a lieutenant at Starbase 24 in 2376
- Matthew Finders, a support staff member on Sheridan's World
- Matthew Gold, grandson of Starfleet captain David Gold
- Matthew Graff, CO of Starbase 12 in 2378
- Matthew Harris, a Section 31 officer
- Matthew Harold, a lieutenant stationed at Cestus III in 2267
- Matthew Kelly, a MACO soldier
- Matthew Kelly (mirror), a MACO officer
- Matthew Mazibuko, a Federation Council representative
- Matthew Nikon, a chief aboard the USS Enterprise
- Matthew O'Hara, CO of the USS Pasteur in 2269
- Matthew Renolds, CO of the USS Polaris in 2284
- Matthew Root, an Earth diplomat in 2063
- Matthew Rose, a 23rd century Starfleet officer
- Matthew Ruiz, a 25th century Starfleet officer
- Matthew Ryan, first officer of the Fortunate in 2151
- Matthew Zavitz, a 24th century teacher
- Ethan Mathews, an Enterprise crewman replaced by a Klingon agent in 2266
- Gabriel Matthews, CO of the USS Hawley in 2285
- P. Matthews, an engineer aboard the USS Arkadelphia
- Todd Matthews, author of the novel Hotel Royale
- Real-world topics
- Matthew Colville, a Decipher RPG author
- Matthew Cushman, a Ships of the Line artist
- See also
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